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While this study was not designed to evaluate the mechanism, it seems to suggest that epigenetic changes could play a role, with reactive oxygen species appearing to be a key contributor that creates the primary source of damage, followed by secondary contributors

AB 11 X2, by Assemblyman Nazarian establishes a tobacco licensing fee program under the state Board of Equalization ANTI-TOBACCO BILL VETOED AB X2 10, by Assemblyman Richard Bloom, D-Santa Monica, allows counties to seek approval from voters to enact local cigarette taxes

10.1001/archderm.135.2.177

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